Each film coated tablet contains:
Centirizine hydrochloride BP 10mg
Cetirizine, a piperazine derivative, is a non-sedating anti-histamine with a potent anti-allergic action. It possesses strong ability for histamine H, receptors and has no anticholinergic and ant-serotoninergic effects. since it does not cross the blood brain barrier it does not cause sedation or interfere with mental alertness or memory function.
Cetramac is indicated in allergic rhinitis, ocular sysmptoms like redness, lacrimination and itching. Urticaria dermographism, atopic eczema and contact dermatitis, acute allergic reactions due to drugs, food, insect bites
Dosage, Contraindication & Adverse Effects
Adult: 10mg once or twice daily.
Children (over 6 years): 5mg or 10mg once daily. or As directed by physician.
Pregnancy, lactation and children.
Certirizine has little or no effect on psychomotor with the incidence of sedation being similar in that of placebo.
The reported adverse reactions at the recommended dosage are low and similar to that of placebo and include drowsiness, dizziness, agitation, dry mouth and gastrointestinal discomfort.
Clinical studies of cetirizine at a dose upto 25mg daily in the healthy volunteers have not revealed effect on alertness or reaction time. Patients are advised not to exceed the recommended dose if driving or operating machinery.
Pregnancy and Lactation:
There is inadequate information about safety of cetirizine during pregnancy. Hence its use in pregnancy is not recommended. Nursing mothers are advised not to take this medication.
Elderly: Some dose reduction may be required, it renal function is impaired
To date, there are no known interactions with other drugs. Nevertheless caution should be recommended with concomitant use of sedatives and alcohol.
STORAGE: Store in a cool dry place.
10×10 Bliester pack